Ingantattun hanyoyin kwantar da hankali: Cututtukan magunguna don ƙirƙirar mafi kyawun hanyoyin kwantar da hankali

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  Quantumrun Haskaka
• Fabrairu 10, 2023

Lokacin yin samfurin magungunan nishaɗi, kowa yana amsawa daban-daban saboda bambancin kwayoyin halitta. Koyaya, kamfanonin fasahar kere kere a yanzu suna ƙirƙirar hanyoyin kwantar da hankali waɗanda aka ƙera don niyya ga yanayin yanayin lafiyar hankali da yawa dangane da kwayoyin halitta. 

Ingantattun mahallin mahallin mahalli

Magungunan ƙwaƙwalwa galibi ana haɗa su da haram, amfani da muggan ƙwayoyi na nishaɗi. Sabili da haka, yawancin binciken kimiyya da likitanci akan waɗannan abubuwa sun mayar da hankali kan mummunan sakamako na zagi. Duk da yake har yanzu ba a sani ba game da magungunan hauka, wani binciken 2020 da aka buga a cikin mujallar Psychological Medicine ya gano yuwuwar fa'idodin warkewa na abubuwa kamar Ayahuasca, ketamine, LSD, MDMA, ko psilocybin don yanayin tabin hankali ciki har da baƙin ciki da rikice-rikicen tashin hankali (PTSD). ). Wadannan psychedelics suna nuna sakamako mai ban sha'awa ga marasa lafiya waɗanda ba su amsa daidaitattun jiyya ba.

Saboda karuwar karɓuwar magungunan ƙwaƙwalwa a matsayin yuwuwar hanyoyin kwantar da hankalin hankali, ƙasashe da yawa sun halatta amfani da su a ƙarƙashin kulawar allurai. Kamfanonin Biotech kuma suna haɓaka hanyoyin da za su ƙara fahimtar kowane mahaɗar mahaukata, ƙayyadaddun kaddarorinsu, da kuma yadda za su iya magance wasu yanayin tunani don haɓaka fa'idodin wannan ci gaba. 

A cewar wani binciken 2017 da aka buga a cikin Neuroscience & Biobehavioral Reviews journal, magungunan psychedelic, irin su ketamine, sau da yawa an samo su don rage tunanin suicidal a marasa lafiya tare da m suicidality. Psilocybin, yawanci a cikin sashi ɗaya, yana haifar da tasiri mai mahimmanci kuma na dogon lokaci na antidepressant ga marasa lafiya waɗanda ba su amsa wasu jiyya ba, a cewar Likitan Ilimin Halitta. Wadannan binciken sun nuna cewa magungunan da aka inganta don wasu bayanan kwayoyin halitta da yanayi na iya samun tasiri mai dorewa.

Tasiri mai rudani

A cikin 2021, New York Mind Medicine (MindMed) ta ba da sanarwar shirye-shiryenta don haɓaka maganin MDMA don tashin hankalin jama'a da cuta ta Autism (ASD). Kamfanin yana gina babban fayil ɗin haɓaka magunguna na sabbin hanyoyin kwantar da hankali dangane da abubuwan tabin hankali, gami da psilocybin, LSD, MDMA, DMT, da kuma 18-MC na ibogaine. MindMed ta ce tana son gano magungunan da ke magance shaye-shaye da cututtukan tabin hankali. 

A halin yanzu babu wasu hanyoyin kwantar da hankali da aka amince da su don ainihin alamun ASD, wanda ke nuna mahimmancin buƙatu na sabbin hanyoyin kwantar da hankali a wannan yanki. Farashin tattalin arzikin ASD a Amurka ana hasashen zai kai dala biliyan 461 nan da shekarar 2025, a cewar MindMed. A halin yanzu, kashi 12 cikin XNUMX na yawan jama'a suna fama da matsalar Damuwar Jama'a a wani lokaci a rayuwarsu, bisa ga Cibiyar Kula da Lafiyar Jama'a ta ƙasa, tana mai jaddada buƙatar ƙarin shiga tsakani.

A cikin 2022, Kimiyyar Rayuwa ta ATAI da ke Jamus ta sanar da cewa ta sami ci gaba sosai wajen haɓaka jiyya na tabin hankali ta hanyar magungunan tabin hankali. Ɗaya daga cikin waɗannan abubuwan haɓakawa shine COMP360 psilocybin far ga mutanen da ke da juriyar jinya. Bugu da ƙari, kamfanin yana duban sake yin amfani da PCN-101 (bangaren ketamine) a matsayin mai saurin yin maganin damuwa da za a iya ɗauka a gida. Ya zuwa yanzu, waɗannan binciken sun nuna cewa za a yi saurin raguwar alamun damuwa a cikin sa'a ɗaya bayan gudanarwa, kuma yana iya yiwuwa har zuwa kwanaki bakwai.

ATAI kuma tana haɓaka jiyya don PTSD ta amfani da abubuwan MDMA. Bugu da ƙari, reshen kamfanin, Revixla Life Sciences, yana nazarin yadda Salvinorin A, wani fili na psychedelic na halitta, zai iya magance matsalolin lafiyar kwakwalwa daban-daban. ATAI ta riga ta fara gwaji da yawa na asibiti a cikin 2022.

Tasirin ingantattun psychedelics

Faɗin tasirin ingantattun psychedelics na iya haɗawa da: 

• Farawa na Biotech suna ƙara mai da hankali kan kasuwar jiyya na tabin hankali, haɗin gwiwa tare da sauran fasahar kere-kere da cibiyoyin bincike.
• Karɓar karɓar magungunan nishaɗi a matsayin hanyoyin kwantar da hankali na halal, rage ɓacin rai da ke tattare da su.
• Masana'antar magunguna ta hauhawa tana fuskantar saurin girma cikin sauri a cikin 2020s, da ingantattun magunguna da kasuwannin jin daɗin jin daɗi.
• Gwamnatoci suna sa ido kan yadda ake gudanar da ingantattun nazarin ilimin mahaukata da gwaje-gwaje don tabbatar da cewa sun kasance masu bin doka da oda. Dangane da sakamakon, za a iya ƙaddamar da ƙarin ƙarin doka don ba da izinin amfani da irin waɗannan kwayoyi a cikin wuraren da aka sarrafa ko ta hanyar iyakanceccen allurai.
• Bambance-bambancen layi tsakanin amfani da magungunan nishaɗi don nishaɗi da magani, wanda zai iya haifar da wasu ruɗewa da wuce gona da iri.

Tambayoyi don yin tsokaci akai

• Ta yaya kuma masana'antar magungunan ƙwaƙwalwa za su amfana daga ingantacciyar kasuwar magunguna?
• Idan kun gwada magungunan kwakwalwa na tushen magunguna, yaya tasiri suke?