Njira zochiritsira zama psychedelic: Kuchepetsa mankhwala kuti apange mankhwala abwino kwambiri

• Author:
• Dzina la wolemba

  Quantumrun Foresight
• February 10, 2023

Potengera mankhwala osangalatsa, aliyense amachita mosiyana chifukwa cha ma genetics osiyanasiyana. Komabe, makampani opanga biotech tsopano akupanga njira zochiritsira zama psychedelic zomwe zimangoyang'ana mitundu ingapo yamatenda amisala kutengera chibadwa. 

Kukonzekera kwa psychedelics

Mankhwala a Psychedelic nthawi zambiri amalumikizidwa ndi kugwiritsa ntchito mankhwala osokoneza bongo, osangalatsa. Chifukwa chake, kafukufuku wambiri wasayansi ndi zamankhwala pa zinthu izi amayang'ana kwambiri zotsatira zoyipa zomwe zingachitike chifukwa cha nkhanza. Ngakhale pali zambiri zosadziwika za mankhwala a psychedelic, kafukufuku wa 2020 wofalitsidwa mu Psychological Medicine magazine wapeza ubwino wochiritsira wa zinthu monga Ayahuasca, ketamine, LSD, MDMA, kapena psilocybin pazochitika zamaganizo kuphatikizapo kuvutika maganizo ndi post-traumatic stress disorder (PTSD). ). Ma psychedelics awa akuwonetsa zotsatira zodalirika kwa odwala omwe sanayankhe chithandizo chokhazikika.

Chifukwa cha kuvomereza kokulirapo kwa mankhwala a psychedelic monga machiritso othekera amisala, mayiko angapo alola kugwiritsira ntchito kwawo mosaloledwa. Makampani opanga sayansi yaukadaulo akhala akupanganso njira zomvetsetsa psychedelic iliyonse, mawonekedwe ake apadera, komanso momwe angathanirane ndi mikhalidwe ina yamalingaliro kuti apindule kwambiri ndi chitukukochi. 

Malinga ndi kafukufuku wa 2017 wofalitsidwa mu Neuroscience & Biobehavioral Reviews magazini, mankhwala osokoneza bongo, monga ketamine, nthawi zambiri amapezeka kuti amachepetsa maganizo ofuna kudzipha mwa odwala omwe akufuna kudzipha kwambiri. Psilocybin, nthawi zambiri pa mlingo umodzi, imapangitsa kuti pakhale zovuta komanso zokhalitsa kwa odwala omwe salabadira chithandizo china, malinga ndi Biological Psychiatry. Zomwe zapezazi zikuwonetsa kuti mankhwala omwe amakongoletsedwa ndi ma genetic komanso mikhalidwe ina amatha kukhala ndi mphamvu kwanthawi yayitali.

Zosokoneza

Mu 2021, Mind Medicine (MindMed) yochokera ku New York idalengeza za mapulani ake opangira chithandizo cha MDMA pamavuto amtundu wa anthu komanso autism spectrum disorder (ASD). Kampaniyo ikupanga gulu lachitukuko chamankhwala chamankhwala atsopano otengera zinthu za psychedelic, kuphatikiza psilocybin, LSD, MDMA, DMT, ndi chochokera ku ibogaine 18-MC. MindMed idati ikufuna kupeza chithandizo chomwe chimalimbana ndi chizolowezi choledzera komanso matenda amisala. 

Pakalipano palibe njira zochiritsira zovomerezeka zazizindikiro zazikulu za ASD, zomwe zikuwonetsa kufunikira kosakwanira kwamankhwala atsopano mderali. Mtengo wachuma wa ASD ku US ukuyembekezeka kufika $461 biliyoni pofika 2025, malinga ndi MindMed. Pakalipano, 12 peresenti ya anthu ambiri amakumana ndi Social Anxiety Disorder panthawi ina m'miyoyo yawo, malinga ndi National Institute of Mental Health, akugogomezera kufunikira kwa njira zowonjezera.

Mu 2022, ATAI Life Sciences yochokera ku Germany idalengeza kuti yapita patsogolo kwambiri popanga chithandizo chamankhwala amisala pogwiritsa ntchito mankhwala osokoneza bongo. Chimodzi mwazinthuzi ndi COMP360 psilocybin therapy kwa anthu omwe ali ndi vuto losamva chithandizo. Kuonjezera apo, kampaniyo ikuyang'ana kukonzanso PCN-101 (gawo la ketamine) ngati mankhwala osokoneza bongo omwe angatengedwe kunyumba. Pakadali pano, kafukufukuyu akuwonetsa kuti zizindikiro za kukhumudwa zitha kuchepetsedwa pakangotha ​​ola limodzi pambuyo pa kuwongolera, ndipo zitha kukhala mpaka masiku asanu ndi awiri.

ATAI ikupanganso chithandizo cha PTSD pogwiritsa ntchito zotumphukira za MDMA. Kuphatikiza apo, othandizira a kampaniyo, Revixla Life Sciences, akuphunzira momwe Salvinorin A, gulu lachilengedwe la psychedelic, limatha kuchiza matenda osiyanasiyana amisala. ATAI yayamba kale mayeso ake angapo azachipatala mu 2022.

Zotsatira za optimized psychedelics

Zotsatira zazikulu za psychedelics wokometsedwa zingaphatikizepo: 

• Kuyamba kwa Biotech kumayang'ana kwambiri msika wamankhwala a psychedelic, kuyanjana ndi ma biotechs ndi mabungwe ofufuza.
• Kuwonjezeka kwa kuvomereza kwa mankhwala osangalatsa monga mankhwala ovomerezeka, kuchepetsa manyazi okhudzana nawo.
• Makampani opanga mankhwala osokoneza bongo a psychedelic akukula mwachangu muzaka zonse za 2020, motsogozedwa ndi misika yokhathamiritsa yamankhwala komanso moyo wapamwamba.
• Maboma omwe amayang'anira momwe maphunziro a psychedelics akukwaniritsidwira ndikuyesa kuwonetsetsa kuti akukhalabe ovomerezeka komanso ovomerezeka. Kutengera ndi zotsatira, malamulo ovomerezeka atha kuperekedwa kuti alole kugwiritsa ntchito mankhwalawa m'malo olamulidwa kapena kudzera mumilingo yochepa.
• Kusawoneka bwino kwa mzere pakati pa kugwiritsa ntchito mankhwala osangalatsa posangalala ndi mankhwala, zomwe zingayambitse kuchulukirachulukira ndi kumwa mopitirira muyeso.

Mafunso oti muyankhepo

• Kodi makampani opanga mankhwala a psychedelic angapindule bwanji ndi msika wokhathamiritsa wamankhwala?
• Ngati mudayesapo chithandizo chamankhwala cha psychedelic, zidathandiza bwanji?