Umuthi we-DIY: Ukuvukela i-Big Pharma

• About the Author:
• Igama lomlobi

  I-Quantumrun Foresight
• June 16, 2022

Ukukhuphuka kwezindleko zemithi ebalulekile efana ne-insulin ne-chenodeoxycholic acid (CDCA) kunikeze ithuba lomuthi we-Do-It-Yourself (DIY), lapho ososayensi nochwepheshe bezempilo bekhiqiza izidakamizwa nemithi yokwelapha bese beyidayisela iziguli ngezindleko. 

DIY umuthi umongo

Ukunyuka kwamanani entengo yemithi ebucayi kanye nokwelashwa kuholele ekutheni amalungu emiphakathi yesayensi nokunakekelwa kwezempilo enze lezi zindlela zokwelapha (uma kungenzeka) ukuze impilo yesiguli ibekwe engcupheni ngenxa yezindleko. E-European Union, izibhedlela zingakhiqiza imithi ethile uma zilandela imithetho ethile. Kodwa-ke, uma izikhungo zokunakekelwa kwempilo ikakhulukazi zigqugquzelwa ukukhiqiza izidakamizwa ngenxa yamanani aphezulu, kubikwa ukuthi zibhekene nokuhlolwa okwengeziwe okuvela kubalawuli bezempilo, nabahloli baqaphe ukungcola kwezinto ezingavuthiwe ezisetshenziswa ukwenza le mithi. Isibonelo, ngo-2019, abalawuli bavala ukukhiqizwa kwe-CDCA eNyuvesi yase-Amsterdam ngenxa yezinto ezingahlanzekile. Kodwa-ke, ngo-2021, i-Dutch Competition Authority yakhipha inhlawulo engu-$20.5 million USD kuLeadiant, umkhiqizi ohamba phambili emhlabeni we-CDCA, ngokusebenzisa kabi isikhundla sawo semakethe ngokusebenzisa amasu entengo eqile.   

Ucwaningo olwenziwa ngo-2018 e-Yale School of Medicine lwathola ukuthi isiguli esisodwa kwezine zesifo sikashukela silinganisela ukusetshenziswa kwaso kwe-insulin ngenxa yezindleko zomuthi, okwandisa ingozi yokwehluleka kwezinso, i-retinopathy yesifo sikashukela, nokufa. E-United States, i-Baltimore Underground Science Space yasungula i-Open Insulin Project ngo-2015 ukuze iphinde iphindaphinde inqubo yokukhiqiza i-insulin yezinkampani ezinkulu ezithaka imithi ziphikisana nezinqubo zokubiza amanani ezeqile zemboni. Umsebenzi wale phrojekthi uvumela iziguli ezinesifo sikashukela ukuthi zithenge i-insulin ngama-dollar ayi-7 ibhodlela, okuwukwehla okuphawulekayo kusuka enanini layo lemakethe lango-2022 eliphakathi kuka-$25 no-$300 ibhodlela (kuya ngemakethe). 

Umthelela ophazamisayo

Amaqembu omphakathi asebenzisana namanyuvesi kanye nabakhiqizi abazimele bemithi ukukhiqiza imithi yokwelapha izifo ezinzima ngenani eliphansi kunabakhiqizi abakhulu bemithi bangase bakhuthaze izinkampani ezinkulu zemithi ukuthi ziguqule amasu azo entengo. Imikhankaso yomphakathi ingase yethulwe noma iqiniswe ngokumelene nalezi zinkampani, kulimaze isithunzi sazo somphakathi futhi kube nomthelela omubi ukuthengiswa kwezidakamizwa. Ngaphezu kwalokho, izinhlangano zomphakathi zingase zinxuse ohulumeni bazo bakazwelonke ukuthi basekele ukukhiqizwa kwezidakamizwa zendawo ukuze kuncishiswe ubungozi bochungechunge lokuhlinzekwa kwempahla kanye nokwakha ukuqina komkhiqizo wezempilo emnothweni wabo. 

Abakhiqizi abakhulu bezidakamizwa abanezikhundla eziphezulu emakethe bangase behlise intengo yemithi ethile ngokusabela kungcindezi yomphakathi noma bafune ukwenza kanjalo ngokushesha ukuze bathuthukise ukuma kwabo emphakathini. Abenzi bomthetho emhlabeni wonke bangase bethule imithethonqubo efinyelela inani lentengo yemithi ethile ukuze abantu bendawo bakwazi ukuyifinyelela ngentengo efanelekile. 

Imithelela yemboni yemithi ye-DIY ekhulayo 

Imithelela ebanzi yezinhlangano zomphakathi kanye nozakwethu bomphakathi abakhiqiza imithi esindisa impilo ngamanani aphansi uma kuqhathaniswa nezinkampani ezinkulu zezidakamizwa ingabandakanya: 

• Abakhiqizi abakhulu be-insulin, abafana no-Eli Lilly, i-Novo Nordisk, ne-Sanofi, behlisa amanani e-insulin, ngaleyo ndlela behlisa imingcele yabo yenzuzo. 
• Izinkampani ezinkulu zemithi zinxenxa ohulumeni bezifundazwe nohulumeni ukuthi balawule ngamandla (futhi bavimbele) ukukhiqizwa kwemithi ekhethiwe yizinhlangano ezingaphandle kwemboni yendabuko yemithi.
• Ukwelashwa kwezimo ezihlukahlukene (njengesifo sikashukela) ukutholakala kalula emiphakathini ehola kancane, okuholela ekwenzeni ngcono imiphumela yokunakekelwa kwezempilo kulezi zindawo.  
• Ukwenyuka kwentshisekelo nasekuthengisweni kwezinto zokusebenza ezikhiqiza imithi ezinhlanganweni zomphakathi kanye nezinkampani ezizimele ezikhiqiza izidakamizwa. 
• Iziqalo ezintsha zobuchwepheshe bezokwelapha zisungulwa ukuze kuncishiswe izindleko nobunkimbinkimbi bokukhiqiza uhla lwemithi.

Imibuzo ongaphawula ngayo

• Ngabe ucabanga ukuthi intengo ye-insulin kufanele ilawulwe emhlabeni wonke? 
• Yibuphi ubungozi obungaba khona bemithi ethile ekhiqizwa endaweni uma kuqhathaniswa nezinkampani ezinkulu ezithaka imithi?