Hair regrowth: New stem cell treatments become possible

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  Quantumrun Foresight
• February 7, 2022

Insight summary

Hair loss is being addressed by recent advancements in stem cell research. Scientists are harnessing human induced pluripotent stem cells to grow natural-looking hair, offering a promising solution for those experiencing hair loss. However, these treatments, while potentially transformative, are still in early development stages and raise important considerations regarding cost, accessibility, safety, and ethical implications.

Hair regrowth context

Hair loss is a common issue that affects over 80 million individuals in the US, spanning across all genders and age groups. The American Academy of Dermatology Association has identified several factors contributing to this condition, including natural aging, genetic predisposition, post-childbirth hormonal changes, and the side effects of cancer treatments. This widespread problem has long been a source of distress for many, impacting self-esteem and overall quality of life. However, recent scientific advancements offer a beacon of hope for those grappling with hair loss.

Scientists have made significant strides in the field of hair regeneration, utilizing human induced pluripotent stem cells (iPSC) to grow natural-looking hair that can penetrate the skin. This technique, which involves reprogramming adult cells into a stem cell-like state, has the potential to significantly alter the landscape of hair growth treatments. The hair produced through this method not only appears natural but also behaves like naturally grown hair, potentially offering a more effective solution for individuals experiencing hair loss. 

The RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has been at the forefront of this research, making significant progress in the quest to find a solution for baldness using stem cells. Their approach involved using whisker cells and fur from mice, combined with various biological ingredients in a laboratory setting. After testing nearly 220 combinations of ingredients, the researchers discovered that a specific blend involving a type of collagen and five other elements—collectively known as the NFFSE medium—resulted in the most rapid and efficient amplification of stem cells. 

Disruptive impact

The potential of stem cell-based treatments for hair loss could have a profound impact on millions of people worldwide who grapple with various forms of hair loss, including female-pattern hair loss (FPHL) and male pattern hair loss (MPHL). This new approach could offer a more effective and natural-looking solution, enhancing the self-esteem and overall quality of life for these individuals. However, it is important to note that the initial costs of these treatments could be high, potentially limiting their accessibility to a broader population. 

In the long term, the development and refinement of stem cell-based treatments could stimulate economic growth and job creation in the biotechnology and healthcare sectors. Companies specializing in hair loss solutions could see a shift in their product offerings and business models, moving away from traditional hair loss treatments towards more advanced stem cell therapies. This development could also lead to increased investment in research and development, fostering a culture of scientific discovery and technological advancement. Governments could play a crucial role in this process, providing funding and regulatory support to ensure these treatments are safe, effective, and accessible to those who need them.

However, while these treatments hold great promise, they are still in the early stages of development, and further research is needed to fully understand their effectiveness and potential side effects. It is crucial that these treatments are thoroughly tested and regulated to ensure patient safety. Moreover, ethical guidelines and policies may need to be established to address potential issues related to the sourcing and use of stem cells.

Implications of hair regrowth

Wider implications of hair regrowth may include:

• Economic growth in the biotechnology sector, leading to increased investment and job creation.


• New ways that people can experiment with their hair styles, leading to the commercialization of these treatments.


• Further exploration into stem cell therapies, leading to advancements in other medical fields.


• New healthcare infrastructure, improving access to advanced medical treatments.


• The high initial costs of these treatments worsening socioeconomic disparities, with only those in higher income brackets able to afford them.


• The increased demand for these treatments putting pressure on natural resources, leading to potential environmental impacts.


• The potential side effects and long-term impacts of these treatments leading to health risks and the need for stringent regulation.

Questions to consider

• When do you think stem cell-based hair regrowth therapies will become available to the wider public?


• Do you think stem cell-based hair regrowth treatments can be more effective than other hair regrowth treatments?


• Can hair regrowth therapies help address the social stigma or emotional trauma of hair loss?